Sleep and Wakefulness Research

The paper identifies that co-activation of the ventral posterolateral nucleus and global brain activity correlates with physiological arousal but not perceptual awareness.

The paper quantifies age-related changes in sleep slow waves using EEG data and a computational model, finding slowed dynamics, increased variability, and reduced amplitude with age.

This study examines the effects of sustained polyphasic sleep restriction on human growth hormone release and other physiological and cognitive measures.

The paper investigates the development of delta-rhythmic activity in the medulla of sleeping infant rats and finds it coincides with cortical delta emergence, suggesting a role for medullary structures in regulating sleep.

This study identifies POA glutamatergic neurons as regulators of stress-induced sleep fragmentation through optogenetic manipulation and calcium activity analysis in mice.

The paper investigates whether sleep can modulate social learning-induced evaluation changes by reactivating memories during sleep, finding that cue-elicited EEG activity predicts enhanced evaluation updates.

This study uses EEG-fMRI to examine age-related changes in cortical and thalamic activity during slow waves in children, showing posterior-to-anterior shifts and thalamic maturation.

This study investigates how Adenosine Kinase affects sleep timing and homeostatic sleep response through distinct molecular pathways in mice.

This study shows sleep loss impairs myelin function by disrupting cholesterol metabolism in oligodendrocytes, leading to conduction delays and motor deficits.

This study finds that phase-amplitude coupling between spindles and slow oscillations during NREM sleep is stable and not affected by pre-sleep learning, but correlates with memory consolidation in a specific learning paradigm.

The paper shows that synaptic strength at hippocampal pathways correlates with vigilance state durations, suggesting sleep architecture influences memory through synaptic modulation.

This study shows that sleep after motor adaptation training improves performance and alters beta oscillations and EEG spectral slope, with sleep spindles predicting success.

The paper investigates EEG correlates of parasomnia experiences and finds similarities with dream-related neural activity.

This study uses spatial transcriptomics to show that sleep deprivation causes region-specific gene expression changes in the brain, with the hippocampus showing the most significant alterations.

This study investigates how sleep affects cerebellar processing in adult mice by examining correlations between muscle twitches, EEG, and climbing fiber activity during different sleep stages.

This study examines how network integration and centrality in the medial temporal lobe during NREM sleep relate to emotional memory retention in older adults.

The paper identifies two substates of REM sleep in mice, showing alternating high and low activation states in the somatosensory pathway involving thalamocortical spindles.

This study shows CBD extends sleep and alters NonREM oscillations in rats, improving sleep but impairing cumulative memory consolidation while leaving simple memory unaffected.

The paper investigates the role of hypocretin neurons in stabilizing sleep by examining their interaction with noradrenergic neurons.

This study tests if memory reactivation during slow wave sleep (SWS) is more effective than during sleep stage 2 (S2), finding no significant difference in memory performance.

This study examines how sleep spindle maturation affects slow oscillation-spindle coupling across different age groups in children.

The paper investigates how individual differences in wake EEG and sleep neurophysiology predict memory consolidation of complex rules in healthy adults.

This study investigates whether targeted memory reactivation during sleep improves motor memory consolidation in older adults, finding no enhancement despite modulation of brain responses to auditory cues.

The paper shows that sleepiness, not total sleep amount, increases seizure risk in Drosophila models by identifying the role of sleep-promoting circuits and serotonin receptors.

This study investigates the role of NPTX2 loss of function in sleep and circadian rhythm disruption, showing that NPTX2 KO mice exhibit disrupted circadian rhythms and sleep fragmentation.

This study shows that suvorexant blocks morphine-induced changes in Hcrt neurons, microglial activation, and anticipatory behavior but preserves morphine analgesia.

This study investigates how claustrum neurons interact with the cortex during different vigilance states, finding that their activity and communication efficacy are modulated by cortical synchronization and cholinergic tone.

The paper characterizes neuronal avalanche criticality during sleep and links it to sleep architecture, showing power law distributions and scaling relations consistent with mean-field directed percolation.

This study investigates how closed-loop auditory stimulation during sleep affects brain activity using magnetoencephalography, finding that ventral frontal regions are critical for slow oscillation generation.

This study shows that D2-MSNs in the lateral ventral striatum induce NREM sleep and coordinate with medial VS D2-MSNs in sleep regulation.