Topic · Oncology · Medicine

Cytokine Signaling Pathways and Interactions

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Immunology·bioRxivPreprint·Aug 24, 2026
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A Cytokine Receptor Signaling Atlas Reveals How STAT Mosaics Fine-Tune T Cell Function
Pingdong Tao, Ruchir Rastogi, Hua Jiang…+4 more authors·K. Christopher García
A fully orthogonal IL-2 receptor platform isolates 36 cytokine receptors in T cells; receptor-specific STAT combinations specify distinct fates, and STAT3-dominant programs give curative antitumor responses.
1 citation
mouse·human
·𝕏 Post·Bluesky