Caveolin-1 and cellular processes

This study shows that lipid packing, particularly cholesterol, influences caveolae stability and dynamics in the plasma membrane.

This study shows Staphylococcus aureus can enter osteoblasts without β1 integrins via vβ3/vβ5 integrins, revealing an alternative internalization pathway.

This study identifies Caveolin-1 as a context-dependent regulator of survival signaling in Ewing Sarcoma, revealing a reversible CD99High state with enhanced survival.

This study uses molecular dynamics simulations to show how the CAV1-8S complex bends membranes and extracts cholesterol, revealing limitations of the Martini v2 forcefield.

This study examines age- and sex-dependent changes in caveolar gene expression in mouse hearts under normoxic and post-ischemic conditions, finding reduced caveolar proteins in males but stability in females, linked to differences in ischemic tolerance.

This study investigates how the absence of Caveolin-1 in fetal brain affects metabolism, epigenetics, and aging in mice by integrating metabolomics, transcriptomics, and single-cell data.

This study shows that loss of Caveolin-1 in zebrafish leads to increased cardiac cell stiffness and impaired heart function, but allows for heart regeneration after injury.