Topic · Molecular Biology · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
6 papers
Masae Horinouchi, Nozomi Kobayashi-Yoshida, Hideaki Nojiri, Hayashi Toshiaki
Malory O. Brown, Paula V. Welander
The paper identifies key residues in bacterial SMTs necessary for sterol side-chain propylation and shows their conservation across methylating, ethylating, and propylating SMTs.
Taojun Wang, Saeed Nazari Soltan Ahmad, Raissa Santos de Lima Rosa…·Jason M. Ridlon
The study identifies Actinobaculum massiliense as a urinary pathobiont capable of generating androgens via the dirAB pathway, using a novel HSDH assay.
Taojun Wang, Briawna Binion, João M. P. Alves, Jason M. Ridlon
This study quantitatively characterizes the kinetic parameters and substrate specificity of the NADPH-dependent 17α-hydroxysteroid dehydrogenase encoded by the desF gene in Clostridium scindens VPI 12708, revealing its role in epitestosterone formation.
This study identifies enzymes involved in C17 propionyl residue removal during steroid degradation in Comamonas testosteroni TA441 and shows structural and functional similarities to Mycobacterium tuberculosis enzymes.