Charles Robin

The paper shows that a tardigrade cytochrome P450 gene disrupts Drosophila melanogaster development when expressed ubiquitously.

The paper investigates evolutionary changes in three enzymes involved in ecdysteroid synthesis across arthropods and correlates these changes with dietary factors.

The paper designs modified Bt Cry1BM and Cry1CM genes for Brassicas to reduce licensing costs and IP issues, showing high insecticidal efficacy in transgenic Arabidopsis.

The paper investigates a gene drive targeting the wupA gene in Drosophila to skew sex ratios, finding it can reduce female progeny and is effective across multiple species.

This paper performs phylogenomic analyses of the EcKL gene family in 140 insect genomes, revealing its role in steroid hormone metabolism and detoxification, with functional shifts linked to host plant diversity.

This study investigates the function of two ecdysteroid kinase-like genes in Drosophila melanogaster using genetic approaches, finding that they may not directly inactivate ecdysteroids but could have novel roles in development.

This paper develops a laboratory model using Drosophila melanogaster to study insecticide susceptibility gene drives, showing they can revert resistance but face challenges like gene drive resistance and population suppression.

This study shows that low doses of spinosad cause lysosomal defects, oxidative stress, lipid dysregulation, and neurodegeneration in Drosophila.

This study identifies EcKL genes in Drosophila melanogaster as detoxification enzymes involved in caffeine and kojic acid tolerance through functional validation and genetic analysis.

The paper identifies candidate detoxification genes in Drosophila by integrating evolutionary and transcriptomic data, finding that EcKLs may function in detoxification and that many P450s are potential detoxification candidates.

The paper identifies cis and trans-acting genetic variants affecting survivorship in Drosophila melanogaster exposed to ryanoid insecticides.

The paper links insecticide resistance in Drosophila melanogaster to structural variants and selective sweep loci using genome-wide association studies.