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The paper analyzes maternal genetic diversity in the Konkani population of India using mitogenomes, revealing distinct haplogroups and historical migration patterns.

This study examines the effects of two mistranslating tRNA variants in Drosophila melanogaster, showing sex-specific impacts on development, lifespan, and locomotion.

This paper introduces a new family of five-leaf admixture tests called {Delta}-statistics to better determine the directionality of admixture compared to existing methods like DFOIL.

The paper identifies genes responsible for metabolic dysfunction-associated steatohepatitis using single-cell eQTL analysis in liver biopsies from MASLD patients and controls.

This paper estimates dominance and selection parameters for nonsynonymous mutations in humans using site frequency spectra and explores their implications for genetic load and inbreeding depression.

This paper demonstrates that simultaneous silencing of intestinal nucleases and a vital gene via dsRNA feeding significantly improves RNAi efficiency and mortality in Mediterranean fruit fly adults.

This study investigates insecticide resistance in Myzus persicae by comparing sensitivity of specific genotypes to various insecticides and screening for resistance mutations.

The paper generates a proteogenomic atlas of the human neural retina using long-read RNA-sequencing and mass spectrometry, identifying novel transcript isoforms and peptides.

The paper analyzes transcriptomic differences in human brain cells with nine high-risk neuropsychiatric CNVs compared to non-carriers, finding widespread gene expression disruptions and shared functional pathways.

The paper identifies a novel OsIAA3-OsARF16-OsBUL1 module that regulates grain size in rice by modulating cell expansion and proliferation.

The paper identifies Skp1 as a conserved structural component of the meiotic synaptonemal complex in nematodes, showing its role in SC assembly and fertility.

The paper explains the sister repulsion phenomenon in Patterson's f-statistics by proposing a demographic model involving gene flow from an external source.

This paper develops and validates variant classification guidelines for animals, improving the accuracy of pathogenicity assessment in cats and eight other species.

The paper identifies EZH2 and SOX2 as key genes in LUAD through differential expression analysis and pathway enrichment, suggesting EZH2 as a potential therapeutic target.

This study shows that inhibiting DNA repair pathways with AZD7648 improves gene insertion efficiency in airway stem cells for CFTR correction, but may introduce toxicity.

The paper responds to criticisms of their reference-free analysis method by addressing claims about high-order epistasis and methodological equivalences.

The paper identifies a locus in one Xiphophorus species that represses an oncogene from another species, providing insights into hybrid incompatibility and pigment cell regulation.

The paper investigates the role of the Raf/LIN-45 C-terminal distal tail segment in regulating signaling in C. elegans, identifying its inhibitory functions through genetic and structural analyses.

The paper investigates the deployment of tethered gene drives in continuous space, finding that drive wave interference must be avoided to ensure successful suppression.

This paper demonstrates the use of CRISPRi/a in zebrafish to modulate gene expression and study gene function in pigmentary and growth phenotypes.