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This study shows that ecdysone negatively regulates size and blocks soldier caste development in Camponotus floridanus, with antagonistic interactions with juvenile hormone and temperature regulation.

The paper develops a cell-free system using Xenopus egg extracts to study TMEJ, showing that Pol theta and Cyclin B-CDK1 are essential for efficient DNA joining.

The paper identifies 588 differentially expressed genes in glaucomatous versus normal trabecular meshwork cells cultured in a soft ECM environment, revealing three disease-related programs.

This study analyzes over 300 plant mitochondrial genomes to show that gene content is conserved but structural complexity varies, driven by repeat proliferation and recombination rather than intergenomic DNA transfer.

This study evaluates how genomic selection can capture polygenic variation from mutation breeding in wheat and tomato, showing improved predictive ability when mutations are shared among lines.

This study shows TMEM55B and TMEM55A regulate lysosome distribution in neurons by affecting motor protein transport, with TMEM55B specifically promoting anterograde transport of LAMP1-positive organelles.

This study maps brainstem-cortical connectivity in aging and prodromal synucleinopathy, finding distinct pathway vulnerabilities in each condition.

Quanta microscopy enables high-speed fluorescence imaging at the native bit-plane rate by reconstructing multibit images from sparse photon-detection maps.

This study investigates whether causal reasoning in the human brain involves a unified system or domain-specific regions, finding distinct brain networks for social and physical causal reasoning.

The paper identifies a subpopulation of highly methylated mtDNA in oocytes, embryos, and blood using single-read methylation analysis, revealing functional heterogeneity among mitochondria.

This study identifies RAP2.6 as a negative regulator of submergence tolerance in Arabidopsis, showing its interaction with GSNOR1-dependent redox and hormonal signaling.

This study identifies the CD44-CD206 axis as a glycoimmune checkpoint that promotes immune exclusion in bladder tumours with immature O-glycosylation.

This study uses MXene nanosheets to capture Alzheimer's disease-associated plasma protein signatures, revealing disease-specific proteomic changes and potential biomarkers.

This study identifies a critical technical limitation in SP-IRIS/IF platforms where non-vesicular artifacts persist after detergent treatment, highlighting the need for detergent lysis controls to ensure accurate single-EV phenotyping.

This study shows that RBFOX2 autoregulation is critical for cardiomyocyte differentiation by maturing the transcriptome, and its disruption leads to congenital heart disease.

The paper identifies Y16 phosphorylation as a conserved switch controlling Ena/VASP recruitment to actin assembly sites, using cell-based reconstitution and biochemical assays.

The paper models how fragmented social networks affect the spread of social behaviors versus infectious diseases, finding that complex contagions are less hindered by subgroup structure than simple contagions.

LDscnR reduces genome scan tests by grouping correlated markers using LD decay, improving precision while maintaining recall, and showing structure can explain outlier regions.

The paper uses live-cell imaging and analysis in mouse embryonic stem cells to show that transcriptional bursting is linked to dynamic merging of enhancer- and promoter-associated regulatory assemblies.

This study explores equitable strategies for participant engagement in rare disease genomic research through interviews with underrepresented individuals and clinicians.