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Nociceptive-evoked electroencephalography can predict inter-individual differences in high frequency induced sensitisation of central nociceptive pathways: A test-retest reliability study

This study evaluates the test-retest reliability of evoked EEG responses during HFS-induced pain and finds poor-to-moderate reliability, with some features showing associations with individual differences in hyperalgesia development.

CloneVI: A deep generative model for deciphering the relationships between cell state and mitochondrial genotype

CloneVI infers clonal structure from cell states in single-cell RNA-seq and ATAC-seq data, linking mitochondrial DNA mutations to specific cell states.

CryoID2: deep learning-enhanced identification of protein and RNA from cryoEM maps

CryoID2 uses deep learning and sequence analysis to identify proteins and RNA from cryoEM maps, achieving high accuracy in molecular identification.

Intestinal molecular siphoning by engineered bacterial spores for non-systemic treatment of nicotine addiction

This paper develops a live bacterial system to reduce nicotine levels in blood and brain by enzymatic degradation in the gut, showing potential for non-systemic treatment of nicotine addiction.

Biological Signaling Pathways Associated with Late Tendon Development in Chicken Embryos and Their Dependence on Mechanical Stimulation

This study identifies mechanotransduction pathways involved in chicken tendon development and shows how paralysis disrupts these processes.

Effects of Reduced Watering Regimes on Hops Growth and Rhizospheric Microbial Communities

This study examines how reduced watering affects hops growth and rhizospheric microbial communities across five cultivars, finding differential plant responses and consistent microbial associations with cultivar type.

A biomimetic SPARC platform coupling adaptor recruitment and BRS-Lck condensation for enhanced NK/T cell combination therapy

Electroencephalographic activity patterns distinguish interdigitated default and frontoparietal networks

The paper identifies distinct electrophysiological patterns in interdigitated default and frontoparietal networks using EEG-fMRI data.

N-GLYcanyzer monitoring of a microperfusion process reveals critical parameters' impact on Trastuzumab biosimilar N-glycoform time evolution

The paper uses N-GLYcanyzer to monitor Trastuzumab biosimilar N-glycoform changes in a microperfusion process, identifying key parameters affecting glycoform evolution.

Optimizing the efficiency of assisted reproduction procedures in the common marmoset (Callithrix jacchus) improved IVF outcomes

This study optimizes IVF procedures in common marmosets by identifying factors like progesterone levels and stimulation duration that improve embryo development and implantation rates.

Species identity rather than colony size partitions shape variation in six Caribbean octocorals

The paper examines colony shape variation in Caribbean octocorals, finding that species identity, not colony size, primarily determines shape differences.

Long-term dysregulation of histone acetylation, BDNF expression, and the hippocampal transcriptome in adult rats exhibiting a depressive-like phenotype following repeated chlorpyrifos exposure

This study shows that repeated chlorpyrifos exposure in rats leads to long-term epigenetic and transcriptional changes in the hippocampus, including reduced BDNF and altered neuronal plasticity pathways, associated with a depressive-like phenotype.

Topographic reference modelling of white matter hyperintensities across the adult lifespan

This paper introduces vTRM, a framework to characterize WMH spatial patterns across age and sex, revealing distinct associations with aging, vascular, and neurodegenerative processes.

Particle-based representation of phytoplankton modulates emergent coexistence and biogeography in a model ocean

This study compares Eulerian and Lagrangian models of phytoplankton communities in an ocean circulation model, showing that particle-based methods produce distinct biogeography and diversity patterns.

GFRAL neurons remodel intestinal structure and type 2 immunity

This study shows that GFRAL neurons in the brainstem regulate intestinal structure and type 2 immunity through a vagal circuit, affecting food allergy, helminth infection, and colitis.

Differential sensing with imprinted and non-imprinted organic electrochemical transistors reduces calibration drift in wearable sweat cortisol sensors

When perfect is a warning: explanations expose shortcuts that accuracy hides in cancer gene-expression classifiers

The paper shows cancer classifiers can achieve perfect accuracy by learning data source shortcuts rather than biological features, and introduces a method to detect and mitigate this issue.

Putative biosurfactants from polar microbial consortia

This study identifies biosurfactant-producing microbial consortia from marine oil snow in western Hudson Bay and finds higher biosurfactant yields at lower temperatures.

Organic Fertilizer Substitution for Chemical Fertilizer Improves Yield, Medicinal Active Compounds and Amino-Acid Profiles of Dendrobium officinale with Multi-Index Comprehensive Evaluation

This study evaluates the effects of organic fertilizer substitution on Dendrobium officinale yield and medicinal quality, finding that 40% substitution optimizes both growth and active compound content.

Bispecific VSV-G Engagers: A Platform for Cell-Type-Specific Delivery of Viral Vectors

This paper develops bispecific VSV-G engagers to enable cell-type-specific delivery of viral vectors, demonstrating effectiveness in targeting tumor cells and generating CAR T cells.