Author

A. A. Al-Hamashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. Chen· 1 shared G. Dong· 1 shared R. Huang· 1 shared Y. Deng· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

D. Chen

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1 paper

Recent·Most cited

BiochemistrybioRxivSep 5, 2020

Discovery of a Potent and Dual-Selective Bisubstrate Inhibitor for Protein Arginine Methyltransferase 4/5

A. A. Al-Hamashi, D. Chen, Y. Deng…·R. Huang

The paper designs and synthesizes a potent dual-selective bisubstrate inhibitor for PRMT4/5, demonstrating high potency and selectivity with IC50 values of 2.8 nM and <1.5 nM.

DOI 10.1016/j.apsb.2020.10.013

experimental assaydrug response / drug discovery

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