Author

A. A. Ritchie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bills· 1 shared A. Cowie· 1 shared A. Hayden· 1 shared A. M. Grabowska· 1 shared A. Manousopoulou· 1 shared A. Silver· 1 shared A. V. Predeus· 1 shared B. Cakir· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Bills

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Author profile →

2 papers

Recent·Most cited

Generation of transplantable and biologically responsive colonic tissue from human induced pluripotent stem cells using a rapid co-differentiation platform.

W. Dalleywater, A. V. Predeus, B. Cakir, P. Mazin, J. Vadakekolathu, S. Rutella, M. L. Meakin, A. A. Ritchie, S. Montazid, S. Cuevas Ocana, N. Holmes, V. Wright, F. Seng, A. Bills, D. Sculthorpe, , M. Ilyas

This paper develops a co-differentiation platform using human iPSCs to generate transplantable colonic tissue that mimics native mucosa and responds to biological signals.

bioRxiv · Dec 8, 2023 · PreprintCell Biology

Modulation of the tumour promoting functions of cancer associated fibroblasts by phosphodiesterase type 5 inhibition increases the efficacy of chemotherapy in human preclinical models of esophageal adenocarcinoma.

A. Hayden, A. Manousopoulou, A. Cowie, R. Walker, B. P. Sharpe, J. Harrington, F. Izadi, E. Kyle, J. H. Saunders, S. L. Parsons, A. A. Ritchie, P. A. Clarke, P. Collier, S. D. Garbis, M. Rose-Zerilli, , T. J. Underwood

This study shows that PDE5 inhibition reduces CAF tumor-promoting effects and enhances chemotherapy efficacy in EAC models.

bioRxiv · Apr 21, 2020 · PreprintCancer Biology