Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma
V. Thoppey Manoharan, A. Abdelkareem, S. Brown, A. Gillmor, C. Hall, H. Seo, K. Narta, S. Grewal, N. H. Dang, B. Y. Ahn, K. Otz, X. Lun, L. Mah, F. J. Zemp, D. J. Mahoney, , S. Morrissy
The paper uses a novel computational workflow to analyze a spatiotemporally profiled GBM xenograft cohort, identifying 15 tumor cell programs related to invasion and their prognostic significance in GBM patients.
bioRxiv · Dec 5, 2023Cancer Biology