Author

A. Alexandrescu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

C. M. Teschke· 1 shared E. B. Gilcrease· 1 shared E. Ng· 1 shared E. R. May· 1 shared H. H. Szeto· 1 shared J. R. Schrad· 1 shared J. Tamucci· 1 shared K. N. Parent· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

C. M. Teschke

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintNov 8, 2021

Structure-Activity Relationships in the Design of Mitochondria-Targeted Peptide Therapeutics

W. Mitchell, J. Tamucci, E. Ng…·N. N. Alder

This study analyzes structure-activity relationships of mitochondria-targeted tetrapeptides, finding that side chain composition and sequence register significantly affect their efficacy and membrane interactions.

DOI 10.1101/2021.11.08.467832

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiophysicsbioRxivFeb 1, 2019

The phage L capsid decoration protein has a novel OB-fold and an unusual capsid binding strategy

R. L. Newcomer, J. R. Schrad, E. B. Gilcrease…·K. N. Parent

The paper determines the structure of the phage L Dec protein and its binding strategy to the capsid using cryo-EM and NMR.

DOI 10.7554/elife.45345

structural biologyexperimental assay

𝕏 PostBluesky