Cell BiologybioRxiv
Epithelial-mesenchymal plasticity induced by discontinuous exposure to TGFβ1 promotes tumour growth
M. Santos, M. Ferreira, P. Oliveira…·C. Oliveira
The paper shows that discontinuous TGFβ1 exposure induces EMT/MET transitions in EpH4 cells, leading to RE-cells with molecular and functional heterogeneity that promotes tumour growth.
DOI 10.3390/biology11071046