Author

A. B. Brummer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

R. C. Rockne· 3 shared C. E. Brown· 2 shared M. Gutova· 2 shared A. Xella· 1 shared C. Brown· 1 shared C. C. Esparza· 1 shared C. Stine· 1 shared E. Ma· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

R. C. Rockne

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Author profile →

3 papers

Recent·Most cited

Model discovery approach enables non-invasive measurement of intra-tumoral fluid transport in dynamic MRI

R. T. Woodall, C. C. Esparza, M. Gutova, M. Wang, J. Cunningham-Reynolds, A. B. Brummer, C. Stine, C. Brown, J. M. Munson, R. C. Rockne

A physics-informed computational method measures fluid dynamics in tumors, showing differences in fluid velocity between breast and brain cancer tissues.

bioRxiv · Aug 28, 2023 · PreprintBioengineering

Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables

A. B. Brummer, A. Xella, R. Woodall, V. Adhikarla, H. Cho, M. B. Gutova, C. E. Brown, R. C. Rockne

This paper applies sparse identification of non-linear dynamics (SINDy) to discover and interpret CAR T-cell interaction dynamics with glioblastoma cells using latent variables.

bioRxiv · Sep 22, 2022Cancer Biology

Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy

A. B. Brummer, X. Yang, E. Ma, M. Gutova, C. E. Brown, R. C. Rockne

This paper uses a mathematical model to show that dexamethasone destabilizes CAR T-cell efficacy in glioblastoma by altering coexistence dynamics and introducing critical thresholds.

bioRxiv · Oct 1, 2021Cancer Biology