J. M. Munson

A physics-informed computational method measures fluid dynamics in tumors, showing differences in fluid velocity between breast and brain cancer tissues.

This study shows that Fusobacterium nucleatum in pancreatic cancer promotes cell proliferation and migration through autocrine and paracrine cytokine signaling.

This paper develops a microfluidic method to create 3D cell cultures with precise spatial organization using photoreactive hydrogels and demonstrates its effectiveness with human T cells.

The paper compares 2D and 3D in vitro cell motility models to assess their predictive power for in vivo cell invasion, finding positive correlations between 2D metrics and 3D migration, and a negative correlation between 3D invasion and glioblastoma in vivo.

This study shows convective flow increases glioblastoma invasion in mice via CXCR4-CXCL12, and CXCR4 antagonists block this effect.

This paper clarifies inconsistent drug response metrics in cancer biomaterial studies and provides best practices for their reporting.