Epigenetic reprogramming of melanoma cell state through fatty acid β-oxidation and Toll like receptor 4 signaling
T.-H. Huang, Y. Ma, E. Montal, S. Suresh, M. M. Tagore, A. Corbin, D. Lumaquin, N. R. Campbell, A. Baggiolini, R. P. Koche, R. M. White
This study shows that fatty acid β-oxidation and TLR4 signaling drive melanoma progression by altering histone acetylation and inflammatory gene expression.
bioRxiv · Jun 16, 2022 · PreprintCancer Biology