Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs (tDRs)
G. Li, A. Manning, A. Bagi, X. Yang, J. Howard, P. P. Chan, T. Sweeney, H. Li, B. D. Laurent, M. I. Kontaridis, L. C. Laurent, K. V. K. Jensen, S. F. Aranki, J. D. Muehlschlegel, R. Kitchen, , S. Das
The paper identifies distinct extracellular tRNA-derived small RNA (tDR) fragmentation signatures associated with different stress responses and shows their potential as biomarkers in human disease.
bioRxiv · Sep 3, 2021Cell Biology