Author

T. Sweeney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. S. Mansur· 2 shared T. Ricciardi-Jorge· 2 shared A. A. dos Santos· 1 shared A. Bafica· 1 shared A. Bagi· 1 shared A. Manning· 1 shared B. D. Laurent· 1 shared B. J. Ferguson· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

D. S. Mansur

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ISG15/USP18/STAT2 is a molecular hub regulating autocrine IFN I-mediated control of Dengue and Zika virus replication

C. E. Espada, E. L. da Rocha, T. Ricciardi-Jorge, A. A. dos Santos, Z. G. Soares, G. Malaquias, D. d. O. Patricio, E. G. Kozlova, P. F. dos Santos, J. Bordignon, T. J. Sanford, T. Fajardo, T. Sweeney, A. Bafica, D. S. Mansur

This paper identifies ISG15/USP18/STAT2 as a molecular hub that regulates autocrine IFN-I signaling to control Dengue and Zika virus replication.

bioRxiv · Nov 1, 2023Immunology

Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs (tDRs)

G. Li, A. Manning, A. Bagi, X. Yang, J. Howard, P. P. Chan, T. Sweeney, H. Li, B. D. Laurent, M. I. Kontaridis, L. C. Laurent, K. V. K. Jensen, S. F. Aranki, J. D. Muehlschlegel, R. Kitchen, , S. Das

The paper identifies distinct extracellular tRNA-derived small RNA (tDR) fragmentation signatures associated with different stress responses and shows their potential as biomarkers in human disease.

bioRxiv · Sep 3, 2021Cell Biology

PKR-mediated Stress Response Enhances Dengue and Zika Virus Replication

T. Ricciardi-Jorge, E. Lummertz da Rocha, E. Gonzalez-Kozlova, G. F. Rodrigues-Luiz, B. J. Ferguson, T. Sweeney, N. Irigoyen, D. S. Mansur

This study shows that PKR-mediated stress response enhances Dengue and Zika virus replication by co-opting the integrated stress response to promote viral mRNA translation.

bioRxiv · Apr 8, 2021Immunology