Genetic Inhibition of Serum Glucocorticoid Kinase 1 Prevents Obesity-related Atrial Fibrillation
A. Bapat, G. Li, L. Xiao, M. Hulsmans, M. J. Schloss, Y. Iwamoto, J. Tedeschi, X. Yang, M. Nahrendorf, A. Rosenzweig, P. Ellinor, S. Das, D. Milan
This study shows that genetic inhibition of SGK1 reduces obesity-related atrial fibrillation in mice by decreasing fibrosis, inflammation, and altering electrophysiology.
bioRxiv · May 20, 2021Physiology