Author

A. Barbieri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 3 Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

R. C. Ford· 3 shared J. P. Manis· 2 shared R. F. Collins· 2 shared T. Shafi· 2 shared A. A. Indzhykulian· 1 shared A. C. Williams· 1 shared A. Karamyshev· 1 shared A. P. Petrashen· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

R. C. Ford

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Humanized V(D)J-rearranging and TdT-expressing Mouse Vaccine Models with Physiological HIV-1 Broadly Neutralizing Antibody Precursors

S. Luo, C. Jing, A. Y. Ye, S. Kratochvil, C. A. Cottrell, J.-H. Koo, A. C. Williams, L. V. Francisco, H. Batra, E. Lamperti, O. Kalyuzhniy, Y. Zhang, A. Barbieri, J. P. Manis, B. F. Haynes, , F. W. Alt

This paper introduces new mouse models expressing human HIV-1 broadly neutralizing antibody (bnAb) precursors with more physiological levels and diversity, enhancing vaccine research for bnAb elicitation.

bioRxiv · Oct 12, 2022Immunology

Structure of ABCB1/P-glycoprotein bound to the CFTR potentiator ivacaftor.

A. Barbieri, N. Thonghin, T. Shafi, S. M. Prince, R. F. Collins, R. C. Ford

This study determines the structure of ABCB1/P-glycoprotein bound to ivacaftor and compares it to the drug-free state to understand binding mechanisms and conformational changes.

bioRxiv · Jun 11, 2021 · PreprintBiochemistry

Integrative analyses uncover mechanisms by which aging drives B cell lymphoma

J. P. Castro, A. V. Shindyapina, A. Barbieri, K. Ying, O. S. Strelkova, J. A. Paulo, A. Tyshkovskiy, R. Meinl, C. Kerepesi, A. P. Petrashen, M. Mariotti, M. Meer, Y. Hu, A. Karamyshev, G. Losyev, , V. N. Gladyshev

This study identifies age-associated clonal B cells (ACBCs) as drivers of B-cell lymphoma in mice, linking aging-related epigenetic and cellular changes to cancer development and proposing mTOR/c-Myc inhibition as a therapeutic strategy.

bioRxiv · Feb 23, 2021 · PreprintCancer Biology

In-vivo crystals reveal protein interactions

E. R. Martin, A. Barbieri, R. C. Ford, R. C. Robinson

The paper develops an in-vivo crystallization system to study protein interactions and applies it to analyze the NHERF1 PDZ2-CFTR complex, revealing new insights into residue-specific binding.

bioRxiv · Sep 26, 2019 · PreprintBiochemistry

Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9A resolution

N. Thongin, R. F. Collins, A. Barbieri, T. Shafi, A. Siebert, R. C. Ford

This study reports novel structural features of P-glycoprotein in the post-hydrolytic state using cryo-EM at 7.9Å resolution, revealing conformational changes and implications for drug transport and resistance.

bioRxiv · Apr 25, 2018Biochemistry