Mechanical stress through growth on stiffer substrates impacts animal health and longevity in C. elegans.
M. Oorloff, A. Hruby, M. Averbukh, A. Alcala, N. Dutta, T. Castro Torres, D. Moaddeli, M. Vega, J. Kim, A. Bong, A. J. Coakley, D. Hicks, J. Wang, T. Wang, S. Hoang, , R. Sanabria
This study investigates the impact of substrate stiffness on C. elegans health and longevity, finding only mild effects on cellular and organismal health.
bioRxiv · Apr 11, 2024Cell Biology