Cell BiologybioRxivPreprint
Orphan nuclear receptor COUP-TFII drives the myofibroblast metabolic shift leading to fibrosis
L. Li, P. Galichon, X. Xiao…·J. V. Bonventre
This study identifies COUP-TFII as a driver of myofibroblast metabolic shift to aerobic glycolysis, promoting fibrosis in multiple organs.