MicrobiologybioRxiv
Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection
Y. Rao, T.-Y. Wang, C. Qin…·P. Feng
This study identifies CTPS1 as a target for antiviral therapy by showing it suppresses interferon induction and promotes viral replication in SARS-CoV-2 infection.
DOI 10.1128/mbio.00649-25