A. C. Steere

HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis

This paper shows that HLA-DR-expressing fibroblast-like synoviocytes can present Lyme autoantigens and activate CD4+ T cells when stimulated with IFN-gamma and Borrelia burgdorferi.

Whole genome sequencing of Borrelia burgdorferi isolates reveals linked clusters of plasmid-borne accessory genome elements associated with virulence.

This study uses whole genome sequencing of Borrelia burgdorferi isolates to identify plasmid-borne accessory genome elements linked to virulence and dissemination of Lyme disease.