PhysiologybioRxivPreprint
Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing and alters beta cell identity in mice
Y.-C. Chen, A. J. Taylor, J. M. Fulcher…·C. B. Verchere
This study shows that deleting CPE in beta cells disrupts proinsulin processing and alters beta cell identity, leading to impaired function and increased beta-cell area in mice.
DOI 10.1101/2022.10.20.512925