Author

A. E. Patterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

C. B. Verchere· 2 shared A. C. Swensen· 1 shared A. J. Taylor· 1 shared A.-S. Archambault· 1 shared E. Tanaka· 1 shared J. Dutra· 1 shared J. H. Oh· 1 shared J. M. Fulcher· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

C. B. Verchere

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Inducing an oxidized redox-balance improves anti-tumor CD8+ T cell function

J. H. Oh, R. A. Cederberg, L. Bopp, E. Tanaka, T. Ser, S. Niyyati, A. E. Patterson, N. Amanat, J. Dutra, P. Ye, M. Clark, K. Ward-Hartstonge, A.-S. Archambault, J. Tsui, P. F. Lange, , R. I. K. Geltink

This study shows that inducing an oxidized redox balance in CD8+ T cells enhances their anti-tumor function in vivo through increased mitochondrial ROS.

bioRxiv · Mar 27, 2023 · PreprintImmunology

Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing and alters beta cell identity in mice

Y.-C. Chen, A. J. Taylor, J. M. Fulcher, A. C. Swensen, X.-Q. Dai, M. Komba, K. L. C. Wrightson, K. Fok, A. E. Patterson, R. I. Klein-Geltink, P. E. MacDonald, W.-J. Qian, C. B. Verchere

This study shows that deleting CPE in beta cells disrupts proinsulin processing and alters beta cell identity, leading to impaired function and increased beta-cell area in mice.

bioRxiv · Oct 20, 2022 · PreprintPhysiology