Dystrophin is a mechanical tension modulator
A. D. Hofemeier, M. Ristau, M. Luber…·T. Betz
This study shows that dystrophin modulates baseline homeostatic tension in skeletal muscle, linking increased tissue tension to DMD pathogenesis.
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4 papers
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A. D. Hofemeier, M. Ristau, M. Luber…·T. Betz
This study shows that dystrophin modulates baseline homeostatic tension in skeletal muscle, linking increased tissue tension to DMD pathogenesis.
H. Schürmann, A. Russo, A. D. Hofemeier…·T. Betz
This study examines mesoscale mechanical forces in podosome clusters of monocytes, revealing that collective behavior arises from network contraction and buckling, not just individual podosome mechanics.
S. Raghuraman, A.-S. Schubert, S. Bröker…·T. Betz
The paper demonstrates that pressure differences inside 3D cancer aggregates drive rapid burst-like collective migration in HeLa cells, independent of ECM pulling forces.
A. D. Hofemeier, T. Limon, T. M. Muenker…·T. Betz
This study introduces a new chamber design for measuring both global and local tension in 3D muscle tissues, revealing early mechanical homeostasis during development.