Author

A. De Angelis

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Carlin· 1 shared A. Clark· 1 shared A. L. Oom· 1 shared B. Croker· 1 shared C. Stoneham· 1 shared D. Castro· 1 shared H. Siddiqi· 1 shared J. Guatelli· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Carlin

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1 paper

Recent·Most cited

BiochemistrybioRxivApr 6, 2021

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

S. H. Park, H. Siddiqi, D. Castro…·S. J. Opella

This study investigates the structure of SARS-CoV-2 E protein and its interactions with amilorides, finding that binding affinity correlates with antiviral activity and that residue Asn15 is critical for maintaining the binding site conformation.

DOI 10.1371/journal.ppat.1009519

humanstructural biology

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