Author

D. Castro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

P. Aguiar· 2 shared V. Nunes· 2 shared A. Carlin· 1 shared A. Clark· 1 shared A. De Angelis· 1 shared A. L. Oom· 1 shared B. Croker· 1 shared C. Stoneham· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

P. Aguiar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

S. H. Park, H. Siddiqi, D. Castro, A. De Angelis, A. L. Oom, C. Stoneham, M. Lewinski, A. Clark, B. Croker, A. Carlin, J. Guatelli, S. J. Opella

This study investigates the structure of SARS-CoV-2 E protein and its interactions with amilorides, finding that binding affinity correlates with antiviral activity and that residue Asn15 is critical for maintaining the binding site conformation.

bioRxiv · Apr 6, 2021Biochemistry

Trackosome: a computational toolbox to study the spatiotemporal dynamics of centrosomes, nuclear envelope and cellular membrane

D. Castro, V. Nunes, J. Lima, J. Ferreira, P. Aguiar

Trackosome tracks centrosomes and reconstructs nuclear and cellular membranes from live-imaging data, revealing correlations between centrosome movements and nuclear envelope oscillations.

bioRxiv · Apr 27, 2020Cell Biology

Mechanosensitive nuclear asymmetries define a bipolar spindle scaffold to ensure mitotic fidelity

V. Nunes, M. Dantas, D. Castro, E. Vitiello, I. Wang, N. Carpi, M. Balland, M. Piel, P. Aguiar, H. Maiato, J. G. Ferreira

The paper shows that nuclear asymmetry during prophase, driven by mechanical cues, enables proper centrosome positioning and bipolar spindle formation for accurate mitosis.

bioRxiv · Nov 18, 2019 · PreprintCell Biology