Cell BiologybioRxiv
Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency
A. Sanchez, A. de Vivo, P. Tonzi…·Y. Kee
This study shows that BMI1 and RNF2 suppress transcription-replication conflicts and CFS instability by regulating RNA Pol II elongation and fork protection.
DOI 10.1371/journal.pgen.1008524