ImmunologybioRxivPreprint
Induction of SARS-CoV-2 N-specific CD8+ T cell immunity in lungs by engineered extracellular vesicles associates with strongly impaired viral replication
F. Manfredi, C. Chiozzini, F. Ferrantelli…·M. Federico
This study shows that engineered extracellular vesicles inducing N-specific CD8+ T cells in lungs reduce SARS-CoV-2 replication in mice, with effects lasting up to three months post-vaccination.
DOI 10.1101/2023.01.19.524762