Cancer BiologybioRxiv
Pharmacological inhibition of nonsense-mediated RNA decay augments HLA class I-mediated presentation of neoepitopes in MSI CRC
J. P. Becker, D. Helm, M. Rettel…·A. E. Kulozik
The paper shows that inhibiting nonsense-mediated RNA decay increases HLA class I presentation of neoepitopes from frameshift mutations in MSI colorectal cancer.
DOI 10.1016/j.isci.2021.102389