Mutant p53 Drives Clonal Hematopoiesis through Modulating Epigenetic Pathway
S. Chen, Q. Wang, H. Yu, M. L. Capitano, S. Vemula, S. C. Nabinger, R. Gao, C. Yao, M. Kobayashi, Z. Geng, A. Fahey, D. Henley, S. Z. Liu, E. R. Wolf, B. Ramdas, , Y. Liu
This study identifies mutant p53's role in promoting clonal hematopoiesis by modulating the EZH2-mediated epigenetic pathway.
bioRxiv · Apr 24, 2019Cancer Biology