Cancer BiologybioRxivPreprint
Mechanistic Elucidation of the Antitumor Properties of a Novel Death Receptor 5 Activator
M. Wang, M. Law, B. Davis…·B. Law
This study identifies DDAs as compounds that upregulate DR5 in cancer cells, leading to apoptosis and synergy with TRAIL, with selectivity for oncogene-transformed cells.
DOI 10.1101/700906