Author

A. Franken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

H. Neubauer· 2 shared M. Rivandi· 2 shared A. Abdollahi· 1 shared A. Antoranz· 1 shared A. Bassez· 1 shared A. Dubrovska· 1 shared A. Linge· 1 shared A. Mukha· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

H. Neubauer

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3 papers

Recent·Most cited

DanioCTC: Injection of circulating tumor cells from metastatic breast cancer patients in zebrafish xenografts for analysis of metastasis

F. Reinhardt, L. Coen, M. Rivandi, A. Franken, E. Sawitning Ayu Setyono, T. Lindenberg, J. Eberhardt, T. Fehm, D. Niederacher, F. Knopf, H. Neubauer

DanioCTC injects patient-derived CTCs into zebrafish embryos to study metastasis, showing distinct dissemination patterns compared to cell line controls.

bioRxiv · Jun 5, 2023 · PreprintCancer Biology

GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy

A. Mukha, U. Kahya, A. Linge, O. Chen, S. Lock, V. Lukiyanchuk, S. Richter, T. C. Alves, M. Peitzsch, V. Telychko, S. Skvortsov, G. Negro, B. Aschenbrenner, I.-I. Skvortsova, P. Mirtschink, , A. Dubrovska

This study shows that glutamine catabolism via GLS regulates redox state, stemness, and autophagy in prostate cancer, affecting radiosensitivity and patient outcomes.

bioRxiv · Jan 7, 2021Cancer Biology

A Pan-Cancer Blueprint of the Heterogeneous Tumour Microenvironment Revealed by Single-Cell Profiling

J. Qian, S. Olbrecht, B. Boeckx, H. Vos, D. Laoui, E. Etlioglu, E. Wauters, V. Pomella, S. Verbandt, P. Busschaert, A. Bassez, A. Franken, M. Vanden Bempt, J. Xiong, B. Weynand, , D. Lambrechts

This study profiles single cells from multiple cancer types to create a pan-cancer blueprint of stromal cell heterogeneity, identifying shared and unique cell populations and their characteristics.

bioRxiv · Apr 1, 2020Cancer Biology