Author

B. Boeckx

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

D. Lambrechts· 4 shared G. Floris· 2 shared A. Alekseenko· 1 shared A. Antoranz· 1 shared A. Bassez· 1 shared A. Claeys· 1 shared A. Franken· 1 shared A. Goga· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCancer Biology

D. Lambrechts

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Respiratory Complex I Regulates Dendritic Cell Maturation in Explant Model of Human Tumor Immune Microenvironment

R. Turpin, R. Liu, P. Munne, A. Peura, J. H. Rannikko, G. Philips, B. Boeckx, N. Salmelin, E. Hurskainen, I. Suleymanova, E. M. Vuorinen, L. Lehtinen, M. Mutka, P. E. Kovanen, L. Niinikoski, , J. Klefstrom

The paper uses a patient-derived explant model to show metformin enhances dendritic cell maturation by inhibiting complex I, improving anti-tumor immunity when combined with venetoclax.

bioRxiv · May 10, 2023Cancer Biology

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

L. Finotto, B. Cole, W. Giese, E. Baumann, A. Claeys, M. Vanmechelen, B. Decraene, M. Derweduwe, N. Dubroja Lakic, G. Shankar, M. Nagathihalli Kantharaju, J. P. Albrecht, I. Geudens, F. Stanchi, K. L. Ligon, , H. Gerhardt

The paper identifies LGALS1 as an immunomodulating target in glioblastoma by analyzing GAM-GBM interactions using single-cell RNA sequencing and zebrafish models.

bioRxiv · Apr 27, 2023 · PreprintCancer Biology

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation

P. Altea-Manzano, G. Doglioni, A. M. Cuadros, E. Nolan, J. Fernandez-Garcia, Q. Wu, F. Cidre-Aranaz, A. Montagne, M. Planque, O. Marin-Bejar, J. Van Elsen, I. Vermeire, D. Broekaert, C. Riera-Domingo, F. Richard, , S.-M. Fendt

This study identifies palmitate-rich metastatic niches as promoters of metastasis by enhancing p65 acetylation and NF-κB signaling in breast cancer cells.

bioRxiv · Oct 24, 2022Cancer Biology

A Pan-Cancer Blueprint of the Heterogeneous Tumour Microenvironment Revealed by Single-Cell Profiling

J. Qian, S. Olbrecht, B. Boeckx, H. Vos, D. Laoui, E. Etlioglu, E. Wauters, V. Pomella, S. Verbandt, P. Busschaert, A. Bassez, A. Franken, M. Vanden Bempt, J. Xiong, B. Weynand, , D. Lambrechts

This study profiles single cells from multiple cancer types to create a pan-cancer blueprint of stromal cell heterogeneity, identifying shared and unique cell populations and their characteristics.

bioRxiv · Apr 1, 2020Cancer Biology