Author

F. Reinhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Plant Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:zebrafish· 2

Frequent Co-Authors

D. Niederacher· 2 shared H. Neubauer· 2 shared R. A. Weinberg· 2 shared T. Fehm· 2 shared A. Brox· 1 shared A. Deik· 1 shared A. E. Cohen· 1 shared A. Franken· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCancer Biology

D. Niederacher

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Author profile →

6 papers

Recent·Most cited

Ether lipids influence cancer cell fate by modulating iron uptake

R. P. Mansell, S. Müller, J.-S. Yang, S. Innes-Gold, S. Das, F. Reinhardt, K. J. Sigmund, V. V. Phadnis, Z. Wan, J. Stark, D. Hwang, F. Sindikubwabo, L. Syx, N. Servant, E. N. Eaton, , W. S. Henry

This study shows that ether lipids in cancer cells regulate membrane properties to influence iron uptake, ferroptosis, and metastasis, offering a therapeutic target.

bioRxiv · Mar 20, 2024Cancer Biology

Chloroplasts lacking class I glutaredoxins are functional but show a delayed recovery of protein cysteinyl redox state after oxidative challenge

F. Bohle, J. Rossi, S. S. Tamanna, H. Jansohn, M. Schlosser, F. Reinhardt, A. Brox, S. Bethmann, S. Kopriva, O. Trentmann, P. Jahns, M. Deponte, M. Schwarzländer, P. Trost, M. Zaffagnini, , S. J. Müller-Schüssele

The paper shows that removing class I GRX activity in the chloroplast stroma of P. patens delays protein cysteine redox recovery after oxidative stress without affecting photosynthesis or NPQ.

bioRxiv · Oct 31, 2023Plant Biology

Lysosomal acid lipase-activity as a novel target to efficiently address triple-negative breast cancer high malignancy

H. Steigerwald, T. Bozzetti, M. Tams, J. On, G. Hoffmann, J. Lambertz, K. Weidele, S. Treitschke, F. Reinhardt, A. Kulik, N. Krawczyk, D. Niederacher, H. Neubauer, C. Werno, T. Rau, , K. Esser

This study shows that inhibiting lysosomal acid lipase (LIPA) reduces breast cancer stemness and sensitizes triple-negative breast cancer (TNBC) cells to chemotherapy, suggesting LIPA as a novel therapeutic target.

bioRxiv · Oct 1, 2023 · PreprintCancer Biology

DanioCTC: Injection of circulating tumor cells from metastatic breast cancer patients in zebrafish xenografts for analysis of metastasis

F. Reinhardt, L. Coen, M. Rivandi, A. Franken, E. Sawitning Ayu Setyono, T. Lindenberg, J. Eberhardt, T. Fehm, D. Niederacher, F. Knopf, H. Neubauer

DanioCTC injects patient-derived CTCs into zebrafish embryos to study metastasis, showing distinct dissemination patterns compared to cell line controls.

bioRxiv · Jun 5, 2023 · PreprintCancer Biology

Profiling extracellular vesicles in circulation enables the early detection of ovarian cancer

H. Lee, D. M. Dinulescu, C. M. Castro, A. Jo, A. Green, J. E. Medina, S. Iyer, A. W. Ohman, E. T. McCarthy, F. Reinhardt, T. Gerton, D. Demehin, R. Mishra, D. L. Kolin, H. Zheng, , B. R. Reuda

This study develops an extracellular vesicle-based test to detect early-stage high-grade serous ovarian cancer with high sensitivity and specificity using markers identified from murine models and validated in a human pilot study.

bioRxiv · Jan 19, 2023 · PreprintCancer Biology

Vernalization alters sugar beet (Beta vulgaris) sink and source identities and reverses phloem translocation from taproots to shoots

C. Martins Rodrigues, C. Müdsam, I. Keller, W. Zierer, O. Czarnecki, J. M. Corral, F. Reinhardt, P. Nieberl, F. Sommer, M. Schroda, T. Mühlhaus, K. Harms, U.-I. Flügge, W. Koch, F. Ludewig, , B. Pommerrenig

This study shows vernalization in sugar beets reverses sink-source dynamics by altering phloem translocation and gene expression, leading to sugar remobilization from taproots to shoots.

bioRxiv · Jan 28, 2020Plant Biology