Author

A. Freywald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

F. S. Vizeacoumar· 3 shared F. J. Vizeacoumar· 2 shared K. Bonham· 2 shared A. Jette· 1 shared A. Jing· 1 shared A. M. Morales· 1 shared A. Scribe· 1 shared B. Haave· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersCancer Biology

F. S. Vizeacoumar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

EPHA1 and EPHB4 tyrosine kinase receptors regulate epithelial morphogenesis

N. Lavoie, A. Scribe, F. J. Chartier, K. Ghani, A. Jette, S. L. Banerjee, M. Caruso, M. Laurin, A. Freywald, S. Elowe, P. Laprise, N. Bisson

This study shows EPHA1 and EPHB4 regulate epithelial morphogenesis by controlling mitotic spindle orientation through ligand-dependent basolateral localization, independent of their catalytic activity.

bioRxiv · Jul 15, 2024 · PreprintCell Biology

MEMO1 is a Metal Containing Regulator of Iron Homeostasis in Cancer Cells

N. Dolgova, E.-M. E. Uhlemann, M. T. Boniecki, F. S. Vizeacoumar, M. Ralle, M. Tonelli, S. A. Abbas, J. Patry, H. Elhasasna, A. Freywald, F. Vizeacoumar, O. Y. Dmitriev

This study identifies MEMO1 as an iron-binding protein that regulates iron homeostasis in cancer cells through interactions with iron-related proteins and its role in ferroptosis.

bioRxiv · Feb 28, 2023Biochemistry

Cancer Cell`s Seven Achilles Heels: Consideration for desing of anti-cancer drug combinations.

V. Gahramanov, F. S. Vizeacoumar, A. M. Morales, K. Bonham, M. K. Sakharkar, F. J. Vizeacoumar, A. Freywald, M. Y. Y. Sherman

The paper identifies seven core pathways as 'Achilles heels' of cancer cells and shows that targeting these pathways can synergize with a diverse range of drugs.

bioRxiv · Jan 2, 2023 · PreprintCancer Biology

Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability

A. Jing, F. S. Vizeacoumar, S. Parameswaran, B. Haave, C. E. Cunningham, Y. Wu, R. Arnold, K. Bonham, A. Freywald, J. Han, F. J. Vizeacoumar

The paper identifies early hypoxia-driven transcriptomic changes in TNBC that promote chromosomal instability and microenvironment remodeling, enabling tumor evolution.

bioRxiv · May 29, 2018Cancer Biology