Author

K. Bonham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Freywald· 2 shared F. J. Vizeacoumar· 2 shared F. S. Vizeacoumar· 2 shared A. Jing· 1 shared A. M. Morales· 1 shared A. Tett· 1 shared A. Zink· 1 shared B. Haave· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. Freywald

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Author profile →

3 papers

Recent·Most cited

Cancer Cell`s Seven Achilles Heels: Consideration for desing of anti-cancer drug combinations.

V. Gahramanov, F. S. Vizeacoumar, A. M. Morales, K. Bonham, M. K. Sakharkar, F. J. Vizeacoumar, A. Freywald, M. Y. Y. Sherman

The paper identifies seven core pathways as 'Achilles heels' of cancer cells and shows that targeting these pathways can synergize with a diverse range of drugs.

bioRxiv · Jan 2, 2023 · PreprintCancer Biology

The Prevotella copri complex comprises four distinct clades that are underrepresented in Westernised populations

A. Tett, K. D. Huang, F. Asnicar, H. Fehlner-Peach, E. Pasolli, N. Karcher, F. Armanini, P. Manghi, K. Bonham, M. Zolfo, F. De Filippis, C. Magnabosco, R. Bonneau, J. Lusingu, J. Amuasi, , N. Segata

The study identifies four distinct clades within the Prevotella copri complex, showing reduced prevalence in Westernised populations compared to non-Westernised ones.

bioRxiv · Apr 9, 2019Microbiology

Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability

A. Jing, F. S. Vizeacoumar, S. Parameswaran, B. Haave, C. E. Cunningham, Y. Wu, R. Arnold, K. Bonham, A. Freywald, J. Han, F. J. Vizeacoumar

The paper identifies early hypoxia-driven transcriptomic changes in TNBC that promote chromosomal instability and microenvironment remodeling, enabling tumor evolution.

bioRxiv · May 29, 2018Cancer Biology