Author

A. G. Alvarado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. I. Kornblum· 3 shared R. Kawaguchi· 2 shared S. D. Muthukrishnan· 2 shared A. Bhaduri· 1 shared A. Deb· 1 shared A. Pham· 1 shared B. W. Kristensen· 1 shared C. A. Wathen· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

H. I. Kornblum

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivJun 19, 2021

Pathway-based approach reveals differential sensitivity of glioblastoma to E2F1 inhibition

A. G. Alvarado, K. Tessema, S. D. Muthukrishnan…·H. I. Kornblum

This study uses pathway analysis to identify E2F1 as a key driver of glioblastoma proliferation and shows its inhibition sensitizes tumors to radiation.

DOI 10.1158/2767-9764.crc-22-0003

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 3, 2021

Radiation-reprogrammed glioma stem cells generate vascular-like cells to build a trophic niche driving tumor recurrence

S. D. Muthukrishnan, R. Kawaguchi, P. Nair…·H. I. Kornblum

The paper shows radiation induces vascular-like phenotypes in glioma stem cells, creating a trophic niche that promotes tumor recurrence, and identifies P300 inhibition as a potential therapeutic strategy.

DOI 10.1101/2021.06.03.447005

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologyJCI InsightPeer-reviewedNov 2, 2018

Global immune fingerprinting in glioblastoma reveals immune-suppression signatures associated with prognosis

T. J. Alban, A. G. Alvarado, M. D. Sorensen…·J. D. Lathia

The paper identifies immune-suppression signatures in glioblastoma (GBM) patients, showing elevated myeloid-derived suppressor cells (MDSCs) linked to poor prognosis and reduced survival.

DOI 10.1172/jci.insight.122264

humanflow cytometry

𝕏 PostBluesky