NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy
A. Choudhury, M. A. Cady, C.-H. G. Lucas, H. Najem, J. J. Phillips, B. Palikuqi, N. Zakimi, T. Joseph, J. O. Birreuta, W. C. Chen, N. A. O. Bush, S. L. Hervey-Jumper, O. D. Klein, C. M. Toedebusch, C. M. Horbinski, , D. R. Raleigh
This study identifies NOTCH3 as a driver of meningioma tumorigenesis and radiotherapy resistance, showing its role in tumor growth and survival in preclinical models.
bioRxiv · Jul 10, 2023 · PreprintCancer Biology