Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
Y.-J. Lin, X. H. M. Tan, Y. Wang, P.-S. Chung, X. Zhang, T.-H. Wu, T.-Y. Wu, A. Deb, E. P. Chiou
This paper introduces a label-free optical mapping platform for large-area biomechanical dynamics of multicellular systems, achieving high spatiotemporal resolution and long-term observations.
bioRxiv · Jun 12, 2024Bioengineering
A. V. Jeyachandran, J. I. Irudayam, S. Dubey, N. Chakravarty, B. Konda, A. Shah, B. Su, C. Wang, Q. Cui, K. J. Williams, S. Srikanth, Y. Shi, A. Deb, R. Damoiseaux, B. Stripp, , V. Arumugaswami
This study compares molecular mechanisms and antiviral targets of Old and New World hantaviruses using human cell models and identifies potential therapeutic compounds.
bioRxiv · Aug 4, 2023 · PreprintMicrobiology
X. H. M. Tan, Y. Wang, X. Zhu, F. N. Mendes, P.-S. Chung, Y. T. Chow, T. Man, H. Lan, Y.-J. Lin, X. Zhang, T. Nguyen, R. Ardehali, M. A. Teitell, A. Deb, P.-Y. Chiou
The paper introduces a high-speed, large-field-of-view platform for measuring sub-cellular traction forces in over 10,000 cells at 83 frames per second.
bioRxiv · Jul 25, 2023 · PreprintBioengineering
R. Pergu, V. M. Shoba, S. K. Chaudhary, D. N. P. M. Godage, A. Deb, S. Singha, U. Dhawa, V. Anokhina, S. Singh, S. U. Siriwardena, A. Choudhary
This paper develops two platforms to create chimeric small molecules that induce tyrosine phosphorylation, demonstrating their ability to trigger phosphorylation and biological activities in target proteins.
bioRxiv · Mar 5, 2023Biochemistry
M. Khamaru, D. Bose, A. Deb, D. Mitra
This study investigates the sequence, structure, and function of Aureochrome bZIP domains using computational and experimental methods, revealing unique features in DNA binding and evolutionary significance.
bioRxiv · May 19, 2022Plant Biology
G. Garcia, Y. Wang, J. I. Irudayam, A. V. Jeyachandran, S. C. Cario, C. Sen, S. Li, Y. Li, A. Kumar, K. Nielsen-Saines, S. W. French, P. S. Shah, K. Morizono, B. Gomperts, A. Deb, , V. Arumugaswami
This study identifies Hippo signaling pathway activation as an antiviral response to SARS-CoV-2 infection and shows pharmacological targeting of the pathway can reduce virus replication.
bioRxiv · Apr 7, 2022Microbiology
T. M. Nguyen, V. Sreekanth, A. Deb, P. Kokkonda, P. K. Tiwari, K. A. Donovan, V. M. Shoba, S. K. Chaudhary, J. A. M. Mercer, S. Lai, A. Sadagopan, M. Jan, E. S. Fischer, D. R. Liu, B. L. Ebert, A. Choudhary
This study develops a platform to identify off-target degradation of ZF proteins by PROTACs and identifies design rules to reduce off-target effects using pomalidomide analogs.
bioRxiv · Nov 18, 2021Pharmacology & Toxicology
T. Bhatt, A. Hegde, R. Dey, A. Ketkar, A. Pulianmackal, A. Deb, S. Rampalli, C. Jamora
This study identifies how mechanical tension in the epidermis triggers DNA methylation changes via DNMT3a, leading to gene expression shifts that initiate wound healing.
bioRxiv · Oct 9, 2021 · PreprintCell Biology
S. D. Muthukrishnan, R. Kawaguchi, P. Nair, R. Prasad, Y. Qin, M. Johnson, N. Vanderveer-Harris, A. Pham, Q. Wang, M. C. Condro, A. G. Alvarado, R. Gau, M. G. Castro, P. R. Lowenstein, A. Deb, , H. I. Kornblum
The paper shows radiation induces vascular-like phenotypes in glioma stem cells, creating a trophic niche that promotes tumor recurrence, and identifies P300 inhibition as a potential therapeutic strategy.
bioRxiv · Jun 3, 2021 · PreprintCancer Biology
F. Aldukhi, A. Deb, C. Zhao, A. S. Moffett, D. Shukla
This study investigates the molecular mechanisms of brassinosteroid binding to the BRI1 receptor using molecular dynamics simulations, revealing differences in binding affinity and conformational changes between two bioactive BRs.
bioRxiv · Oct 7, 2019Plant Biology