Conformations of the Human Immunodeficiency Virus (HIV-1) Envelope Glycoproteins in Detergents and Styrene-Maleic Acid Lipid Particles (SMALPs)
R. Zhou, S. Zhang, H. T. Nguyen, H. Ding, A. Gaffney, J. C. Kappes, A. B. Smith, J. G. Sodroski
This study compares the stability and conformation of HIV-1 Env in detergents versus SMA lipids, showing SMA preserves the pretriggered state better at room temperature.
bioRxiv · Mar 1, 2023 · PreprintMicrobiology