H. T. Nguyen

This study develops ten elite tomato lines through conventional breeding, showing improved agronomical traits and virus resistance for agricultural use.

The paper shows that expressing broadly or poorly neutralizing antibodies or CD4 in HIV-1-producing cells reduces viral infectivity by disrupting Env processing and incorporation into virions.

This study improves neoantigen prediction by integrating RNA sequencing data with DNA sequencing to identify more immunogenic neoantigens in colorectal cancer patients.

The paper develops an in vitro assay to determine phosphatase specificity and applies it to study mitotic exit, revealing substrate preferences and biological relevance.

This paper develops a transferable model to predict biophysical properties of IDPs, showing agreement with experimental data on size, conformation, and SAXS profiles.

The paper develops isogenic head and neck cancer cell line pairs to study Fanconi anemia-associated cancers and their treatment.

This study compares the stability and conformation of HIV-1 Env in detergents versus SMA lipids, showing SMA preserves the pretriggered state better at room temperature.

The paper shows that odd-even differences in RNA repeat sequences affect phase separation propensity through free energy gaps between ground and slipped hairpin states.

The paper investigates the function of OsCOI2 in rice, showing it plays a specialized role in jasmonate-dependent root growth inhibition, distinct from OsCOI1a and OsCOI1b.

This paper characterizes HIV-1 Env conformational states on virions and shows how stabilizing the pretriggered State-1 conformation enhances bNAb recognition and reduces shedding.

This study finds a negative correlation between soybean yield and the number of nucleotide-binding leucine-rich repeat (NLR) resistance genes.

The paper develops personalized breast cancer models to identify biomechanical factors affecting drug penetration and discovers potential therapeutic targets.

The paper shows that changes in the MPER of HIV-1 Env lead to premature triggering and increased neutralization sensitivity, which can be counteracted by distant State 1-stabilizing Env modifications.

This study maps haplotype variation at the cqProt-003 locus in soybean, identifying structural variants and tandem repeats associated with high protein content and tracing their distribution across wild, landrace, and cultivated populations.

This study identifies key features of the SARS-CoV-2 spike glycoprotein, including the furin cleavage site and D614G mutation, that influence viral infectivity, stability, and cytopathicity.

This paper tests a natural oil blend (NOBF) against ASFV in porcine alveolar macrophages, finding it deactivates the virus at high dilutions.

The paper identifies PP2A-B55's role in meiosis I to II transition through selective dephosphorylation of threonine residues in sea star oocytes.

This study shows that divalent cations bind to RNA in a nucleotide-specific manner through inner or outer shell coordination, with Mg2+ preferring outer shell and Ca2+ inner shell, and bridging interactions playing a key role in RNA folding.

The paper identifies core transcription factors regulating root growth in soybean under water deficit by integrating phylogenetic analysis and transcriptome data.

This study identifies a non-canonical Hippo pathway in yeast meiosis II that regulates spindle disassembly and cytokinesis through SPS1 and CDC15.

This paper develops a theory and simulation approach to accurately predict RNA folding in mixed ion solutions, showing good agreement with experimental data.

This study develops a high-content method to assess HER2 overexpression and amplification at the cell level in breast cancer tissues to detect intratumoral heterogeneity.