Author

A. Goff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. B. Lanne· 1 shared A. Blair· 1 shared A. Feula· 1 shared A. Yoshizawa· 1 shared B. P. Towler· 1 shared C. Huard· 1 shared C. Neagoie· 1 shared C. Press· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

A. B. Lanne

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Author profile →

3 papers

Recent·Most cited

β-Catenin associates with a Wnt signaling mRNA network in myeloid cells through canonical RBP binding.

M. Wagstaff, O. Sevim, A. Goff, M. Raynor, H. Park, E. Mancini, D. T. Nguyen, T. Chevassut, A. Blair, L. Castellano, S. F. Newbury, B. P. Towler, R. G. Morgan

The paper identifies β-catenin-associated mRNAs in myeloid cells through RIP-seq and shows MSI2 interacts with LEF1 mRNA, regulating Wnt signaling and HSPC expansion.

bioRxiv · Jan 28, 2024 · PreprintCell Biology

Fisetin Attenuates Cellular Senescence Accumulation During Culture Expansion of Human Adipose-Derived Stem Cells

M. T. Mullen, A. Goff, J. Billings, H. Kloser, C. Huard, J. Mitchell, W. S. Hambright, S. Ravuri, J. Huard

This study shows fisetin reduces senescence markers in cultured human adipose-derived stem cells while preserving their differentiation potential.

bioRxiv · Nov 15, 2022Cell Biology

Azetidines kill Mycobacterium tuberculosis without detectable resistance by blocking mycolate assembly.

A. B. Lanne, Y. Cui, E. Browne, P. G. E. Craven, N. J. Cundy, N. J. Coltman, K. Dale, A. Feula, J. Frampton, A. Goff, M. A. Hama Salih, X. Lang, X. Li, C. W. Moon, M. Morton, , L. J. Alderwick

The paper identifies azetidine derivatives that kill Mycobacterium tuberculosis without resistance by inhibiting mycolate assembly, showing a novel mode of action and favorable pharmacological profiles.

bioRxiv · Sep 3, 2020 · PreprintMicrobiology