Author

T. Chevassut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Blair· 1 shared A. E. Davis· 1 shared A. Goff· 1 shared A. Newcombe· 1 shared A.-L. Latif· 1 shared B. Higgens· 1 shared B. P. Towler· 1 shared C. McKeeve· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Blair

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Author profile →

2 papers

Recent·Most cited

β-Catenin associates with a Wnt signaling mRNA network in myeloid cells through canonical RBP binding.

M. Wagstaff, O. Sevim, A. Goff, M. Raynor, H. Park, E. Mancini, D. T. Nguyen, T. Chevassut, A. Blair, L. Castellano, S. F. Newbury, B. P. Towler, R. G. Morgan

The paper identifies β-catenin-associated mRNAs in myeloid cells through RIP-seq and shows MSI2 interacts with LEF1 mRNA, regulating Wnt signaling and HSPC expansion.

bioRxiv · Jan 28, 2024 · PreprintCell Biology

BRD4-mediated repression of p53 is a target for combination therapy in AML

A.-L. Latif, A. Newcombe, S. Li, K. Gilroy, N. Robertson, X. Lei, H. Stewart, J. Cole, M. T. Terradas, L. Rishi, L. McGarry, C. McKeeve, C. Reid, W. Clark, J. Campos, , P. D. Adams

This study shows that combining MDM2 inhibitors and BET inhibitors synergistically kills AML cells by enhancing p53 activation through BRD4's repressive function.

bioRxiv · Sep 16, 2020Cell Biology