Cell BiologybioRxivPreprint
Dual Dysfunction of Kir2.1 Underlies Conduction and Excitation-Contraction Coupling Defects Promoting Arrhythmias in a Mouse Model of Andersen-Tawil Syndrome Type 1
A. Macias, A. Gonzalez-Guerra, A. I. Moreno-Manuel…·J. Jalife
This study identifies a dual dysfunction of Kir2.1 in a mouse model of ATS1, linking it to conduction and excitation-contraction coupling defects that promote arrhythmias.
DOI 10.1101/2021.06.17.448833