Cell BiologybioRxivPreprint
HD mutation results in a dominant negative effect on HTT function
T. L. Laundos, S. Li, E. Cheang…·A. H. Brivanlou
This study shows that HD mutations cause a dominant negative effect on HTT function by inducing HD-like phenotypes in non-HD cells.
DOI 10.1101/2023.06.26.543767