BiochemistrybioRxiv
Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation
X. Jia, Y. K.- Y. Chin, A. H. Zhang…·M. Mobli
This paper introduces autocyclase proteins that enable efficient self-cyclisation of peptides and proteins, producing cyclic biomolecules with high yields and avoiding challenges of enzymatic methods.
DOI 10.1038/s42004-023-00841-5