Differential Histone-DNA Interactions Dictate Nucleosome Recognition of the Pioneer Transcription Factor Sox
B. Ozden, R. Boopathi, A. B. Barlas, I. N. Lone, J. Bednar, C. Petosa, S. Kale, A. Hamiche, D. Angelov, S. Dimitrov, E. Karaca
This study shows that Sox PTF recognizes nucleosomes through distinct histone-DNA interactions, with specific reading mechanisms at different superhelical locations.
bioRxiv · Dec 7, 2021 · PreprintBiophysics